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Cholesterol

  • Overview

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    Cholesterol is a waxy substance found in the blood that is necessary for building healthy cells. However, high levels of cholesterol can increase the risk of heart disease. When cholesterol levels are elevated, fatty deposits can accumulate in the blood vessels, narrowing and reducing blood flow. In some cases, these deposits can rupture and form a clot, resulting in a heart attack or stroke.

    While high cholesterol can have a genetic component, it is often the result of unhealthy lifestyle choices, making it preventable and treatable. Adopting a healthy diet, exercising regularly, and maintaining a healthy weight are important steps in managing cholesterol levels. However, in some cases, medication may be necessary to help reduce high cholesterol.

    Medications such as statins, fibrates, bile acid sequestrants, and cholesterol absorption inhibitors can be prescribed to lower cholesterol levels. These medications work through different mechanisms to reduce the production or absorption of cholesterol in the body. 

    Regular monitoring of cholesterol levels through blood tests is essential to assess the effectiveness of lifestyle changes and medication. By managing high cholesterol effectively, individuals can reduce their risk of heart disease and improve their overall cardiovascular health.

  • Symptoms

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    High cholesterol typically does not cause any noticeable symptoms. It is often called a “silent” condition because individuals can have high cholesterol levels without experiencing any specific signs or symptoms. Therefore, a blood test is the only reliable way to detect if you have high cholesterol.

    A lipid profile blood test is commonly used to measure cholesterol levels. This test measures different types of cholesterol, including total cholesterol, LDL (low-density lipoprotein) cholesterol, HDL (high-density lipoprotein) cholesterol, and triglycerides. These measurements provide a comprehensive assessment of your cholesterol profile.

    It is recommended to have regular cholesterol screenings as part of routine preventive healthcare, especially if you have risk factors for high cholesterol or heart disease. Risk factors include a family history of high cholesterol or heart disease, obesity, a sedentary lifestyle, a diet high in saturated and trans fats, smoking, and certain medical conditions such as diabetes or hypothyroidism.

  • When to see a doctor

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    According to the National Heart, Lung, and Blood Institute (NHLBI), it is recommended that individuals have their first cholesterol screening between the ages of 9 and 11. After the initial screening, it is advised to repeat the test every five years. However, the frequency of cholesterol screenings may vary depending on individual risk factors.

    For adults, the NHLBI recommends cholesterol screenings every one to two years for men between the ages of 45 and 65, and for women between the ages of 55 and 65. Individuals over the age of 65 should have cholesterol tests annually.

    If your cholesterol test results are outside the desirable ranges, your doctor may recommend more frequent measurements to monitor your cholesterol levels closely. Additionally, suppose you have a family history of high cholesterol, heart disease, or other risk factors such as diabetes or high blood pressure. In that case, your doctor may also suggest more frequent cholesterol tests to assess your cardiovascular health.

    Your doctor might also suggest more frequent tests based on your medical history, family history, and overall health status. Regular cholesterol screenings are crucial for early detection and management of high cholesterol, which can help reduce the risk of heart disease and other related complications.

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  • Causes

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    Cholesterol is carried through the blood attached to proteins, forming lipoproteins. There are different types of cholesterol based on the lipoprotein they are carried by:

    • Low-density lipoprotein (LDL): Known as the “bad” cholesterol, LDL transports cholesterol particles throughout the body. It can build up in the artery walls, leading to the narrowing and hardening of arteries.
    • High-density lipoprotein (HDL): Referred to as the “good” cholesterol, HDL picks up excess cholesterol and transports it back to the liver for processing.

    In addition to cholesterol, a lipid profile also measures triglycerides, a type of fat in the blood. Elevated triglyceride levels can increase the risk of heart disease.

    Inactivity, obesity, and an unhealthy diet, contribute to harmful cholesterol and triglyceride levels. However, it is important to note that genetic factors can also influence cholesterol metabolism. Genetic variations may make it more challenging for the body to remove LDL cholesterol from the blood or break it down in the liver. Understanding the interplay between genetic and lifestyle factors is crucial in managing cholesterol levels effectively.

  • Risk factors

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    Several factors can increase your risk of having unhealthy cholesterol levels. These include:

    • Poor diet: Consuming excessive amounts of saturated fat or trans fats can lead to unhealthy cholesterol levels. Saturated fats are commonly found in fatty cuts of meat and full-fat dairy products. Trans fats are often present in packaged snacks or desserts.
    • Obesity: Having a body mass index (BMI) of 30 or higher puts you at a greater risk of developing high cholesterol levels.
    • Lack of exercise: Regular physical activity can help increase your body’s HDL levels, which is often referred to as the “good” cholesterol.
    • Smoking: Cigarette smoking has been shown to lower the HDL cholesterol levels, which is beneficial for your health.
    • Alcohol consumption: Drinking excessive amounts of alcohol can raise your overall cholesterol levels.
    • Age: While even young children can have unhealthy cholesterol levels, it is more commonly observed in individuals over 40. As you age, your liver becomes less efficient at removing LDL cholesterol from your body.

    By being aware of these risk factors, you can take proactive steps to maintain healthy cholesterol levels and reduce your risk of developing related health issues.

  • Prevention

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    Lifestyle changes that are beneficial for lowering cholesterol levels can also be effective in preventing high cholesterol from occurring in the first place. To help prevent high cholesterol, you can:

    • Follow a low-salt diet that focuses on consuming plenty of fruits, vegetables, and whole grains. These foods are rich in nutrients and fibre, which can help maintain healthy cholesterol levels.
    • Limit your intake of animal fats and incorporate good fats in moderation. Good fats, such as those found in nuts, seeds, and avocados, can be beneficial for your heart health when consumed in appropriate amounts.
    • Maintain a healthy weight by losing any excess pounds. Being overweight or obese can increase your risk of developing high cholesterol levels.
    • Quit smoking. Smoking not only lowers the levels of “good” cholesterol in your body but also damages your blood vessels, increasing the risk of heart disease.
    • Engage in regular exercise for at least 30 minutes on most days of the week. Physical activity helps raise your “good” cholesterol levels and promotes overall cardiovascular health.
    • If you choose to drink alcohol, do so in moderation. Excessive alcohol consumption can contribute to high cholesterol levels, so limiting your intake is important.
    • Manage stress effectively. Chronic stress can have negative effects on your overall health, including cholesterol levels. Find healthy ways to cope with stress, such as through relaxation techniques or engaging in activities you enjoy.

    By incorporating these lifestyle changes into your daily routine, you can significantly reduce your risk of developing high cholesterol and promote a heart-healthy lifestyle.

  • *Please note that the information provided in the article is for reference purposes only. It is essential to consult a doctor before applying any of the suggestions mentioned.

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Last updated on: 11/10/2023