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Malaria

  • Overview

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    Malaria, caused by a parasite transmitted through mosquito bites, leads to debilitating symptoms such as high fever and severe chills. Though less prevalent in temperate regions, it remains a significant health concern in tropical and subtropical regions. Annually, approximately 290 million people contract malaria, with over 400,000 fatalities attributed to the disease.

    Global health initiatives combat malaria through various strategies, including the distribution of preventive medications and bed nets treated with insecticides to deter mosquito exposure. The World Health Organization has endorsed a malaria vaccine for children in high-risk countries, aiding in the disease’s containment.

    When traveling, protective measures like wearing appropriate clothing, using bed nets, and applying insecticides offer safeguards. Preemptive medication is advisable before, during, and post-travel to high-risk zones. Notably, many malaria strains exhibit resistance to conventional treatment drugs, underscoring the ongoing challenge of managing the disease.

  • Symptoms

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    Common signs and symptoms associated with malaria encompass:

    • Fever
    • Chills
    • General sense of discomfort
    • Headache
    • Nausea and vomiting
    • Diarrhea
    • Abdominal pain
    • Muscle or joint pain
    • Fatigue
    • Rapid breathing
    • Rapid heart rate
    • Cough

    Malaria may prompt cyclical “attacks” in certain individuals. These attacks generally commence with shivering and chills, followed by a pronounced fever, and culminate in sweating and a return to normal body temperature.

    Typically, malaria indications and symptoms manifest within a few weeks following a mosquito bite from an infected insect. Nevertheless, certain strains of malaria parasites can lay dormant within the body for as long as a year.

  • When to see a doctor

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    Abnormal symptoms may be a warning sign of potential dangerous diseases. Please contact our team of doctors immediately for detailed advice and update the most accurate and appropriate health care method.

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  • Causes

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    Malaria is attributed to a singular-celled parasite known as plasmodium, belonging to the genus Plasmodium. The primary mode of transmission to humans is predominantly via mosquito bites.

    Transmission through Mosquito Cycle

    Mosquitoes become infected when they feed on an individual carrying the malaria parasite. Subsequently, when the infected mosquito bites another person, it transmits the parasites into their bloodstream. These parasites then journey to the liver, mature, and eventually infect red blood cells, triggering the onset of malaria symptoms. If another mosquito bites the infected person during this stage, it becomes a carrier of the parasite and can spread it to others through subsequent bites. This intricate cycle underscores the crucial role of mosquitoes in malaria transmission.

    The propagation of malaria is facilitated by an intricate cycle involving mosquitoes:

    1. Infection of Mosquito: A mosquito contracts the disease by feeding on an individual already infected with malaria.
    2. Parasite Transmission: If the same mosquito bites another individual in the future, it can transmit the malaria parasites to them.
    3. Transition in the Liver: The parasites infiltrate the individual’s body and migrate to the liver, where certain strains can remain dormant for up to a year.
    4. Bloodstream Invasion: Upon maturation, the parasites exit the liver and invade red blood cells. This is typically when malaria symptoms begin to manifest.
    5. Transmission Continues: Should an uninfected mosquito bite the infected individual at this stage, it becomes host to the malaria parasites and can subsequently spread them to others through subsequent bites.

    Other Modes of Transmission

    Given that the malaria-causing parasites target red blood cells, alternative transmission routes include:

    • From an infected mother to her unborn child
    • Through blood transfusions
    • Via shared needles used for drug injection
  • Risk factors

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    Living in or visiting regions where malaria is endemic presents the highest risk for contracting the disease. These regions encompass tropical and subtropical areas in:

    • Sub-Saharan Africa
    • South and Southeast Asia
    • Pacific Islands
    • Central America and northern South America

    The level of risk is influenced by local malaria control efforts, seasonal fluctuations in malaria prevalence, and personal preventive measures against mosquito bites.

    Certain individuals face a greater risk of severe illness, including:

    • Young children and infants
    • Elderly individuals
    • Travelers arriving from non-endemic areas
    • Pregnant women and their unborn offspring

    In regions with high malaria rates, limited access to preventative measures, medical care, and information exacerbates the issue.

    While residents of endemic regions may develop partial immunity over time, reducing the severity of symptoms, this immunity can diminish upon relocating to a lower-exposure area.

  • Prevention

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    If you reside in or are planning to travel to a malaria-endemic area, adopting measures to prevent mosquito bites is crucial. Mosquitoes are most active during dusk and dawn. To safeguard yourself against mosquito bites, consider the following steps:

    1. Cover Your Skin: Wear long-sleeved shirts and pants, with your shirt tucked in and pant legs tucked into socks.
    2. Apply Insect Repellent to Skin: Utilize an EPA-registered insect repellent on exposed skin. Recommended repellents include those containing DEET, picaridin, IR3535, oil of lemon eucalyptus (OLE), para-menthane-3,8-diol (PMD), or 2-undecanone. Refrain from directly applying repellent to your face, and avoid using products with OLE or PMD on children under three years old.
    3. Apply Repellent to Clothing: Safely apply sprays with permethrin to your clothing.
    4. Sleep Under a Net: Make use of bed nets, particularly those treated with insecticides like permethrin, to shield against mosquito bites while sleeping.

     

    Additionally, if you’re heading to a malaria-prone region, consult your doctor several months in advance about the advisability of taking medication before, during, and after your trip. This precautionary medication helps guard against malaria parasites. The choice of medication depends on various factors, including your travel duration, destination, and individual health.

    Furthermore, a malaria vaccine recommended by the World Health Organization is available for children residing in high-malaria-burden countries. Ongoing research continues to refine and develop malaria vaccines as preventive measures against infection.

  • *Please note that the information provided in the article is for reference purposes only. It is essential to consult a doctor before applying any of the suggestions mentioned.

Content Details

Medical info from Mayo Clinic, for reference only. Visit Hoan My for better advice.

Last updated on: 06/08/2023