Factor V Leiden is a genetic mutation affecting one of the clotting factors in the blood. This mutation may raise the possibility of developing abnormal blood clots, which typically occur in the legs or lungs. However, most individuals with factor V Leiden never experience abnormal clots. Nonetheless, those who do may face long-term health issues or life-threatening situations.
Factor V Leiden can affect both men and women. Women who carry this mutation may have a greater chance of developing blood clots during pregnancy or when taking estrogen hormone. If you have this mutation and have experienced blood clots, anticoagulant medications can reduce the risk of developing further blood clots and help prevent serious complications.