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Factor V Leiden

  • Overview

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    Factor V Leiden is a genetic mutation affecting one of the clotting factors in the blood. This mutation may raise the possibility of developing abnormal blood clots, which typically occur in the legs or lungs. However, most individuals with factor V Leiden never experience abnormal clots. Nonetheless, those who do may face long-term health issues or life-threatening situations.

    Factor V Leiden can affect both men and women. Women who carry this mutation may have a greater chance of developing blood clots during pregnancy or when taking estrogen hormone. If you have this mutation and have experienced blood clots, anticoagulant medications can reduce the risk of developing further blood clots and help prevent serious complications.

  • Symptoms

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    It is important to note that the factor V Leiden mutation exhibits no symptoms. However, it increases the risk of developing blood clots in the legs or lungs. Therefore, the first sign of the disorder may be the emergence of an abnormal blood clot. While some clots dissolve independently without complications, others can be fatal. The symptoms of a blood clot depend on the affected area of the body.

    If you experience pain, swelling, redness, or warmth in your legs may be a sign of deep vein thrombosis (DVT). This condition happens when blood clots form in the deep veins of your legs. Although DVT can be asymptomatic, it can also lead to life-threatening complications. A DVT can break free and travel to your lungs, causing a pulmonary embolism. Signs of this include sudden shortness of breath, chest pain when breathing in, and a cough with bloody or blood-streaked sputum. If you experience any of these symptoms, it’s essential to seek medical attention immediately.

  • When to see a doctor

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    If you experience any signs or symptoms of a DVT or a pulmonary embolism, you must immediately seek medical attention. Your health is too important to take any chances with, so don’t hesitate to get the help you need. Remember, early detection and treatment are critical to a successful recovery.

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  • Causes

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    If you have Factor V Leiden, in rare cases, you have inherited a defective gene either from one parent or from both parents. Having one copy of the gene will slightly increase the chances of developing blood clots while having two copies will significantly increase the risk of blood clots.

  • Risk factors

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    If your family has a history of Factor V Leiden, your chances of inheriting the disorder are higher. This condition is most prevalent among people of European descent. People who inherit factor V Leiden from one parent have a 5% chance of developing abnormal blood clots by age 65. Factors that can increase this risk include having two mutated genes, extended periods of immobility like long flights, estrogen intake from oral contraceptives, hormone replacement therapy, pregnancy, surgeries or injuries such as broken bones, and having a non-O blood type. People with A, B or AB blood types are more likely to develop abnormal blood clots than those with O.

  • Prevention

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    If you have Factor V Leiden, a genetic condition that increases the risk of blood clots, it’s crucial to take action to prevent them from forming. One of the best ways to do this is to maintain a healthy lifestyle, which includes regular exercise, a well-balanced diet, and abstaining from smoking. Your doctor may also prescribe medications, such as blood thinners, to prevent blood clots from occurring. To ensure that you’re taking the appropriate steps to minimise your risk of blood clots, it’s essential to speak with your healthcare provider and address any concerns about Factor V Leiden prevention.

  • *Please note that the information provided in the article is for reference purposes only. It is essential to consult a doctor before applying any of the suggestions mentioned.

Content Details

Medical info from Mayo Clinic, for reference only. Visit Hoan My for better advice.

Last updated on: 14/08/2023