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Allergy medications

  • Overview

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    Allergic reactions manifest when the body’s immune system responds against foreign substances, such as pollen, bee venom, pet dander, or even certain foods that typically do not trigger reactions in most individuals.

    In these instances, the immune system becomes a key player by producing specialised molecules known as antibodies. In the case of allergies, the immune system generates antibodies designed to recognise and flag a specific allergen as harmful, even when it poses no real threat. Subsequently, when an individual encounters the allergen, their immune system mounts a response that can lead to inflammation in various body parts, including the skin, sinuses, airways, or digestive system.

    It is crucial to note that the severity of allergic reactions can significantly differ from person to person. These variations span a spectrum, ranging from mild irritations to severe episodes, potentially culminating in a life-threatening condition known as anaphylaxis—an emergency requiring immediate attention.

    Regrettably, while there is currently no cure for most allergies, various treatment modalities exist to alleviate the distressing symptoms associated with these immune responses, providing individuals with a means to manage and improve their quality of life despite allergies.

  • Symptoms

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    The presentation of allergy symptoms is contingent upon the specific substance to which an individual is exposed. These symptoms can impact multiple bodily systems, including the respiratory airways, sinuses, nasal passages, skin, and the digestive system. Recognising that the spectrum of allergic reactions encompasses a wide range of severity, from mild manifestations to grave instances, is paramount.

    In certain severe cases, allergies can incite a hazardous and potentially fatal response termed “anaphylaxis.” This severe allergic reaction necessitates immediate medical intervention to avert life-threatening consequences.

    1. Hay fever

    Hay fever, also known as allergic rhinitis, is a condition that can give rise to a constellation of distressing symptoms. These symptoms typically include:

    • Sneezing: Individuals afflicted by hay fever often experience frequent and sometimes uncontrollable bouts of sneezing.
    • Itching: Itching sensations can manifest in various areas, including the nose, eyes, or even the roof of the mouth, adding to the discomfort associated with hay fever.
    • Nasal discomfort: Hay fever commonly results in a runny or stuffy nose, making it challenging for affected individuals to breathe comfortably.
    • Ocular affliction: The eyes are also vulnerable to hay fever’s effects, often becoming watery, red, and occasionally swollen—conjunctivitis.

    2. A food allergy 

    Beyond being a matter of dietary concern, food allergies can provoke an array of adverse reactions that significantly impact an individual’s life, extending to their nutritional choices, social interactions, and overall well-being. These allergies manifest through various  symptoms, including:

    • Tingling sensations: Food allergies can trigger tingling sensations within the mouth, causing discomfort and often alerting individuals to an allergenic substance in their food.
    • Swelling: Swelling is another hallmark affecting various facial features, including the lips, tongue, face, or throat. This swelling can be uncomfortable and potentially dangerous, mainly when it involves the throat.
    • Hives: The appearance of hives, characterised by itchy, raised, and often red welts on the skin, is a common manifestation of food allergies. Hives can be distressing and contribute to the discomfort experienced during an allergic reaction.
    • Anaphylaxis: In the most severe cases, food allergies can lead to a life-threatening condition known as anaphylaxis. Anaphylactic reactions demand immediate medical attention due to their potential to cause a rapid decline in overall health, including severe respiratory and cardiovascular distress.

    3. An insect sting allergy:

    An allergy to insect stings can evoke a spectrum of severe and, in some cases, life-threatening responses in individuals who exhibit sensitivity to insect venom. These reactions can encompass localised symptoms and  more generalised manifestations, including:

    • Localised oedema: Individuals with an insect sting allergy may experience a substantial swelling, known as oedema, at the site of the sting. This localised response can result in significant discomfort and is often an early sign of an allergic reaction.
    • Pruritus and hives: The allergic response can extend beyond the sting site, leading to widespread itching or the development of hives, which are raised, itchy welts that can emerge across various body areas.
    • Respiratory distress: Insect sting allergies can also affect the respiratory system, potentially causing symptoms such as coughing, chest tightness, wheezing, or difficulty breathing (shortness of breath). These respiratory symptoms are indicative of a more systemic reaction to the allergen.
    • Anaphylaxis: In the most severe instances, an insect sting allergy can culminate in a life-threatening condition known as anaphylaxis. Anaphylaxis necessitates immediate medical intervention due to its potential to induce a rapid and catastrophic decline in overall health, with symptoms encompassing severe airway constriction and cardiovascular compromise.

    4. A drug allergy

    A drug allergy can give rise to a diverse array of adverse reactions and complications, significantly impacting an individual’s health. These reactions can encompass a spectrum of symptoms, including:

    • Hives: Hives, characterised by itchy, raised welts on the skin, is a common manifestation of drug allergies. They can appear suddenly and contribute to considerable discomfort.
    • Itchy skin: Individuals with drug allergies may experience generalised itching of the skin, which can be distressing and persistent.
    • Rash: The development of a rash is another hallmark symptom, often presenting as red, inflamed skin that may be accompanied by itching and discomfort.
    • Facial swelling: Facial swelling is a concerning symptom that can occur in response to a drug allergy. This swelling may involve the lips, tongue, or other facial features, potentially leading to airway obstruction in severe cases.
    • Respiratory symptoms: Drug allergies can affect the respiratory system, causing wheezing, characterised by high-pitched, whistling sounds during breathing. These respiratory symptoms can range from mild to severe.
    • Anaphylaxis: In the most severe instances, drug allergies can precipitate anaphylaxis, a life-threatening allergic reaction that demands immediate medical intervention. Anaphylaxis can manifest as a rapid and severe deterioration in overall health, with symptoms including severe airway constriction, cardiovascular instability, and other systemic effects.

    5. Atopic dermatitis

    Atopic dermatitis, commonly referred to as eczema, is an allergic skin condition notorious for disrupting the skin’s normal functioning. This condition can induce a range of distressing skin changes, including:

    • Pruritus (Itch): One of the hallmark characteristics of atopic dermatitis is an intense, persistent itch that can be incredibly discomforting. Itching often compels individuals to scratch their skin, exacerbating the condition.
    • Reddening of the skin: The skin affected by atopic dermatitis tends to become red and inflamed, further contributing to the discomfort and visual changes associated with the condition.
    • Flaking and peeling: Eczematous skin often changes texture, leading to flakiness and peeling. These alterations can result in a rough, scaly appearance and may be accompanied by dryness.

    6. Anaphylaxis

    Certain allergies, notably those triggered by specific foods or insect stings, have the potential to instigate a grave and potentially life-threatening condition known as anaphylaxis. Anaphylaxis constitutes a medical emergency of the utmost seriousness, with the potential to induce shock. Signs and symptoms indicative of anaphylaxis encompass:

    • Loss of consciousness: Anaphylaxis can lead to a sudden loss of consciousness, rendering the affected individual unresponsive.
    • Hypotension (drop in blood pressure): One of the hallmark features of anaphylaxis is a significant drop in blood pressure, which can result in circulatory compromise and systemic dysfunction.
    • Severe respiratory distress: Individuals experiencing anaphylaxis often exhibit severe shortness of breath, manifesting as difficult breathing or difficulty drawing in sufficient air.
    • Cutaneous manifestations: Skin changes, such as the development of a rash, may occur during anaphylaxis, contributing to the overall clinical picture.
    • Lightheadedness: Lightheadedness or dizziness is a common symptom in anaphylaxis, often linked to a drop in blood pressure and impaired oxygenation.
    • Cardiovascular impairment: A rapid and weak pulse is a frequent cardiovascular manifestation of anaphylaxis, underscoring the severe systemic impact of the condition.
    • Gastrointestinal distress: Anaphylaxis can also lead to nausea and vomiting, further complicating the clinical presentation.
  • When to see a doctor

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    If you are experiencing symptoms that you suspect may be related to an allergy and over-the-counter allergy medications fail to provide adequate relief, you should schedule an appointment with your healthcare provider. Additionally, if you develop symptoms shortly after starting a new medication, it is crucial to contact the healthcare professional who prescribed it without delay.

    Immediate action is imperative for a severe allergic reaction, such as anaphylaxis. You should take the following steps:

    • Call 115 or your local emergency number: In cases of anaphylaxis, which can rapidly escalate and become life-threatening, it is essential to call for emergency medical assistance promptly .
    • Use your epinephrine Auto-Injector: If you carry an epinephrine auto-injector , administer the injection immediately. Epinephrine (Adrenalin) can help counteract the severe symptoms of anaphylaxis and buy time for further medical treatment.
    • Seek further medical attention: Even if your symptoms appear to improve after the epinephrine injection, seeking additional medical care at an emergency department is crucial. This step is essential to ensure that your symptoms do not return once the effects of the epinephrine wear off, as anaphylactic reactions can have a rebound effect.

    Timely and appropriate medical intervention is pivotal in managing allergies, particularly severe allergic reactions, to mitigate potential complications and safeguard your well-being.

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  • Causes

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    Allergies originate from a pivotal event where the immune system erroneously identifies an ordinarily harmless substance as a potential threat. This misidentification leads to the production of specialised antibodies primed to recognise and combat this specific allergen. Subsequently, upon reexposure to the allergen, these antibodies can instigate the release of various immune system chemicals, notably histamine, which, in turn, precipitate the characteristic symptoms of an allergic reaction.

    Common allergy triggers encompass a broad spectrum of substances, including:

    • Airborne allergens: Substances like pollen, animal dander, dust mites, and mould spores are among the culprits responsible for allergic reactions when inhaled. These airborne allergens can lead to symptoms affecting the respiratory system and skin.
    • Food allergens: Certain foods tend to trigger allergies, with notable culprits including peanuts, tree nuts, wheat, soy, fish, shellfish, eggs, and milk. Food allergies can induce various symptoms, from gastrointestinal distress to skin reactions and respiratory issues.
    • Insect stings: Stings from insects like bees or wasps can provoke allergic reactions in susceptible individuals. These reactions can vary in severity, with some leading to anaphylaxis, a potentially life-threatening condition.
    • Medications: Specific medications, particularly those containing penicillin or penicillin-based antibiotics, can incite allergic reactions. Such reactions may manifest as skin rashes, respiratory distress, or other symptoms.
    • Contact allergens: Substances like latex or other materials that come into direct contact with the skin can trigger allergic reactions, often presenting as skin rashes or irritation.
  • Risk factors

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    Several factors can increase an individual’s likelihood of developing allergies. These risk factors include:

    • Family history: A family history of asthma or allergies, such as hay fever, hives, or eczema, can significantly heighten the risk of developing allergies. Genetic predispositions and shared environmental factors can play a role in this increased susceptibility.
    • Age: Allergies are more commonly observed in children, with many individuals developing their first allergic reactions during childhood. However, allergies can also manifest in adulthood, and their prevalence may vary.

    Coexisting allergic conditions: Individuals with asthma or other allergies may be at an increased risk of developing additional allergies. This phenomenon is sometimes called the “allergic march,” where one allergic condition may pave the way for others.

  • Prevention

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    The prevention of allergic reactions is contingent upon an individual’s specific type of allergy. Nevertheless, general preventive measures  can be beneficial for managing allergies, including :

    • Avoiding known triggers: Avoiding known allergenic triggers is paramount for individuals with allergies. For example, if you’re allergic to pollen, staying indoors with windows and doors closed during peak pollen seasons is advisable. Likewise, individuals allergic to dust mites can benefit from frequent dusting, vacuuming, and regular washing of bedding.
    • Maintaining a symptom diary: Keeping a detailed record of your activities, dietary choices, symptom onset times, and any relief measures can be invaluable in identifying triggers and patterns related to your allergies. This information can assist both you and your healthcare provider in pinpointing the specific factors contributing to your allergic reactions.
    • Medical alert bracelet: If you’ve experienced severe allergic reactions in the past, wearing a medical alert bracelet (or necklace) is a prudent safety measure. These identifiers alert healthcare providers and others to your severe allergies, which can be crucial in a sudden, painful reaction when you cannot communicate.

    Individualised allergy prevention and management strategies may vary based on the specific allergen and individual circumstances. It is advisable to work closely with a healthcare provider, particularly an allergist or immunologist, to develop a comprehensive plan tailored to your unique allergy profile. This collaborative approach can optimise allergy management and enhance your quality of life.

  • *Please note that the information provided in the article is for reference purposes only. It is essential to consult a doctor before applying any of the suggestions mentioned.

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Last updated on: 09/10/2023