Diseases & Conditions
Easy-to-understand answers about diseases and conditions
X-linked agammaglobulinemia (XLA) is an inherited immune system disorder that impairs your infection-fighting ability. This condition primarily affects males, though females can carry the genetic mutation. XLA makes individuals susceptible to infections in the inner ear, sinuses, respiratory tract, bloodstream, and internal organs. Diagnosis often occurs during infancy or early childhood due to recurrent infections, but some cases may not be identified until adulthood. It’s crucial for carriers of the genetic mutation to be aware of the potential risks and to seek medical guidance for early detection and management.