Diseases & Conditions
Easy-to-understand answers about diseases and conditions
Zollinger-Ellison syndrome is an uncommon disorder marked by the growth of one or more tumors known as gastrinomas, typically found in the pancreas or the upper segment of the small intestine. These gastrinomas excrete excessive amounts of the hormone gastrin, which triggers excessive stomach acid production, leading to the development of peptic ulcers. Elevated gastrin levels can also result in symptoms like abdominal pain, diarrhea, and discomfort. While Zollinger-Ellison syndrome can manifest at any life stage, it’s most commonly diagnosed between ages 20 and 60. Standard treatment involves medications to curtail stomach acid and facilitate ulcer healing. In some cases, surgical removal of tumors may be necessary.