Acute myelogenous leukemia

In the initial stages, acute myelogenous leukemia may display symptoms similar to the flu or other common illnesses. Some signs and symptoms of acute myelogenous leukemia are:
Fever
Bone pain
Lethargy and fatigue
Shortness of breath
Pale skin
Frequent infections
Easy bruising
Unusual bleeding, such as frequent nosebleeds and bleeding from the gums

You must schedule an appointment with a doctor if you notice any unusual or concerning signs or symptoms. They can help you determine the cause and provide the necessary treatment to get you feeling better. Don’t hesitate to contact a medical professional if you have any concerns.

Acute myelogenous leukemia is a type of cancer that occurs when a bone marrow cell experiences changes or mutations in its genetic material (DNA). DNA serves as a cell’s instructions, dictating growth rates and lifespan. In the case of acute myelogenous leukemia, the mutations cause bone marrow cells to continue dividing and growing uncontrollably.

As a result, the production of blood cells spirals out of control. Immature cells are produced, which develop into leukemic white blood cells known as myeloblasts. These abnormal cells fail to function correctly, and they can accumulate and displace healthy cells.

It is unclear what causes the DNA mutations that lead to leukemia, but doctors have identified risk factors that increase the likelihood of developing it.

Factors that may increase your risk of acute myelogenous leukemia (AML) include:
Increasing age. The risk of acute myelogenous leukemia increases with age. Acute myelogenous leukemia is most common in adults aged 65 and older.
Your sex. Men are more likely to develop acute myelogenous leukemia than are women.
Previous cancer treatment. People with certain types of chemotherapy and radiation therapy may have a greater risk of developing AML.
Radiation exposure. People exposed to very high radiation levels, such as survivors of a nuclear reactor accident, have an increased risk of developing AML.
Dangerous chemical exposure. Exposure to certain chemicals, such as benzene, is linked to a greater risk of AML.
Smoking. AML is linked to cigarette smoke containing benzene and other known cancer-causing chemicals.
Other blood disorders. People with different blood disorders, such as myelodysplasia, myelofibrosis, polycythemia vera or thrombocythemia, are at greater risk of developing AML.
Genetic disorders. Certain genetic diseases, such as Down syndrome, are associated with an increased risk of AML.

Many people with AML have no known risk factors, and many people with risk factors never develop cancer.